These are VKORC1 CDS sequences in brown rats. 
The resistant alleles are resistant to warfarin.
Rats with the WildType sequence die from warfarin poisoning.

NOTE *** = Active site of protein 
NOTE XXX = Warfarin binding site

LABEL 394 "*********"
LABEL 412 "XXXXXXXXX"

GENETIC_CODE = Standard




#WildType
ATGGGCACCACCTGGAGGAGCCCTGGACGTTTGCGGCTTGCACTATGCCTCGCTGGCCTAGCCCTCTCACTGTACGCACTGCACGTGAAGGCGGCGCGCG
CCCGCAATGAGGATTACCGCGCGCTCTGCGACGTGGGCACGGCCATCAGCTGTTCCCGCGTCTTCTCCTCTCGGTGGGGCCGGGGCTTTGGGCTGGTGGA
GCATGTGTTAGGAGCTGACAGCATCCTCAACCAATCCAACAGCATATTTGGTTGCATGTTCTACACCATACAGCTGTTGTTAGGTTGCTTGAGGGGACGT
TGGGCCTCTATCCTACTGATCCTGAGTTCCCTGGTGTCTGTCGCTGGTTCTCTGTACCTGGCCTGGATCCTGTTCTTTGTCCTGTATGATTTCTGCATTG
TTTGCATCACCACCTATGCCATCAATGCGGGCCTGATGTTGCTTAGCTTCCAGAAGGTGCCAGAACACAAGGTCAAAAAGCCCTGA


#Resistant_Tyr139Cys
ATGGGCACCACCTGGAGGAGCCCTGGACGTTTGCGGCTTGCACTATGCCTCGCTGGCCTAGCCCTCTCACTGTACGCACTGCACGTGAAGGCGGCGCGCG
CCCGCAATGAGGATTACCGCGCGCTCTGCGACGTGGGCACGGCCATCAGCTGTTCCCGCGTCTTCTCCTCTCGGTGGGGCCGGGGCTTTGGGCTGGTGGA
GCATGTGTTAGGAGCTGACAGCATCCTCAACCAATCCAACAGCATATTTGGTTGCATGTTCTACACCATACAGCTGTTGTTAGGTTGCTTGAGGGGACGT
TGGGCCTCTATCCTACTGATCCTGAGTTCCCTGGTGTCTGTCGCTGGTTCTCTGTACCTGGCCTGGATCCTGTTCTTTGTCCTGTATGATTTCTGCATTG
TTTGCATCACCACCTGTGCCATCAATGCGGGCCTGATGTTGCTTAGCTTCCAGAAGGTGCCAGAACACAAGGTCAAAAAGCCCTGA


#Resistant_Tyr139Phe
ATGGGCACCACCTGGAGGAGCCCTGGACGTTTGCGGCTTGCACTATGCCTCGCTGGCCTAGCCCTCTCACTGTACGCACTGCACGTGAAGGCGGCGCGCG
CCCGCAATGAGGATTACCGCGCGCTCTGCGACGTGGGCACGGCCATCAGCTGTTCCCGCGTCTTCTCCTCTCGGTGGGGCCGGGGCTTTGGGCTGGTGGA
GCATGTGTTAGGAGCTGACAGCATCCTCAACCAATCCAACAGCATATTTGGTTGCATGTTCTACACCATACAGCTGTTGTTAGGTTGCTTGAGGGGACGT
TGGGCCTCTATCCTACTGATCCTGAGTTCCCTGGTGTCTGTCGCTGGTTCTCTGTACCTGGCCTGGATCCTGTTCTTTGTCCTGTATGATTTCTGCATTG
TTTGCATCACCACCTTTGCCATCAATGCGGGCCTGATGTTGCTTAGCTTCCAGAAGGTGCCAGAACACAAGGTCAAAAAGCCCTGA


#Resistant_Tyr139Ser
ATGGGCACCACCTGGAGGAGCCCTGGACGTTTGCGGCTTGCACTATGCCTCGCTGGCCTAGCCCTCTCACTGTACGCACTGCACGTGAAGGCGGCGCGCG
CCCGCAATGAGGATTACCGCGCGCTCTGCGACGTGGGCACGGCCATCAGCTGTTCCCGCGTCTTCTCCTCTCGGTGGGGCCGGGGCTTTGGGCTGGTGGA
GCATGTGTTAGGAGCTGACAGCATCCTCAACCAATCCAACAGCATATTTGGTTGCATGTTCTACACCATACAGCTGTTGTTAGGTTGCTTGAGGGGACGT
TGGGCCTCTATCCTACTGATCCTGAGTTCCCTGGTGTCTGTCGCTGGTTCTCTGTACCTGGCCTGGATCCTGTTCTTTGTCCTGTATGATTTCTGCATTG
TTTGCATCACCACCTCTGCCATCAATGCGGGCCTGATGTTGCTTAGCTTCCAGAAGGTGCCAGAACACAAGGTCAAAAAGCCCTGA