Michael Snyder

Speaker: Michael Snyder, Ascherman Professor and Chair of the Department of Genetics, Director of the Center of Genomics and Personalized Medicine,
Stanford University

Date: Thursday, February 25, 2016
Time: 5:30 PM
Place: Hager Auditorium, Museum of the Rockies

Title: Personalized Medicine: New Directions to Revolutionize Management of Health and Disease

Summary:

We are undergoing a revolution unlike any other in biology and medicine. It is now possible to have your DNA sequence (genome) decoded and take billions of measurements of your molecular composition and activities. This information will transform how your health is managed and how medicine is practiced.

About the speaker:

Michael Snyder is the Stanford Ascherman Professor and Chair of Genetics and the Director of the Center of Genomics and Personalized Medicine. Dr. Snyder received his Ph.D. training at the California Institute of Technology and carried out postdoctoral training at Stanford University. He is a leader in the field of functional genomics and proteomics, and one of the major participants of the ENCODE project. His laboratory study was the first to perform a large-scale functional genomics project in any organism, and has developed many technologies in genomics and proteomics. These including the development of proteome chips, high resolution tiling arrays for the entire human genome, methods for global mapping of transcription factor binding sites (ChIP-chip now replaced by ChIP-seq), paired end sequencing for mapping of structural variation in eukaryotes, de novo genome sequencing of genomes using high throughput technologies and RNA-Seq. These technologies have been used for characterizing genomes, proteomes and regulatory networks. Seminal findings from the Snyder laboratory include the discovery that much more of the human genome is transcribed and contains regulatory information than was previously appreciated, and a high diversity of transcription factor binding occurs both between and within species. He has also combined different state-of-the-art "omics" technologies to perform the first longitudinal detailed integrative personal omics profile (iPOP) of person and used this to assess disease risk and monitor disease states for personalized medicine. He is a cofounder of several biotechnology companies, including Protometrix (now part of Life Technologies), Affomix (now part of Illumina), Excelix, and Personalis, and he presently serves on the board of a number of companies.