Characteristics
Morphology
Fungus belonging to the Trichocomaceae family. Colonies grow rapidly, producing white green, yellow, or black colonies
Growth Conditions
Potato dextrose agar
Health Hazards
Host Range
Humans, animals, and birds.
Modes of Transmission
Inhalation, through contaminated water, and nosocomial infections (hospital fabrics and plastics)
Signs and Symptoms 
Fever, facial pain, headache, asymmetric facial swelling, epistaxis, proptosis, cranial nerve abnormalities.
Infectious Dose Unknown.
Incubation Period 
2 days to 3 months
Medical Precautions/Treatment
Prophylaxis None.
Vaccines None.
Treatment
Voriconazole, amphotericin B, posaconazole and echinocandins. Is resistant to itraconazole and some isolates have been reported to be resistant to voriconazole, posaconazole and echinocandins.
Surveillance Monitor for symptoms.
MSU Requirements Report any exposures.
Laboratory Hazards
Laboratory Acquired Infections (LAIs)
None reported
 Sources
Sput, biopsy material, transtracheal aspirates, blood, and soil.
Inhalation of air contaminated with
Aspergillus spores.
Supplemental References
BMBL:5th Edition http://www.cdc.gov/biosafety/publications/bmbl5/BMBL.pdf
Canadian MSDS
http://www.phac-aspc.gc.ca/lab-bio/res/psds-ftss/index-eng.php
CDC
Containment Requirements
BSL2 For all procedures involving known or potentially infected cultures.
ABSL2 For all procedures utilizing infected animals.
Spill Procedures
Small Notify others working in the lab. Remove and don new PPE. Cover area of the spill with absorbent material and add 10 % Bleach. Allow 30 minutes hour of contact time. After 30 minutes and then cleanup and dispose of materials.
Large
For assistance, contact MSU's Biosafety Officer: Ryan Bartlett, ryan.bartlett@montana.edu, (406) 994-6821
or Safety and Risk Management (406-994- 2711).
Exposure Procedures
Mucous membrane
Flush eyes, mouth or nose for 5 minutes at eyewash station.
Other Exposures
Wash area with soap and water for 5 minutes.
Reporting
Immediately report incident to supervisor, complete a first report of injury report, and submit to Safety and Risk Management.
Medical Follow-up
During business hours: Bridger Occupational Health 3406 Laramie Drive. Weekdays 8am -6pm.  Weekends 9am-5pm
After business hours: Bozeman Deaconess Hospital Emergency Room 915 Highland Blvd Bozeman, MT
Viability
Disinfection
Susceptible to 10 % Bleach, 70 % ethanol.
Inactivation
Inactivated by dry heat (1 hour at 160-170 C).
Survival Outside Host
Can survive in soil and decomposing vegetation.
Personal Protective Equipment (PPE)
Minimum PPE Requirements
At minimum, gloves, closed toed shoes, lab coat, and appropriate face and eye protection prior to working with Aspergillus fumigatus. Additional PPE may be required depending on lab specific SOPs.
Additional Precautions
Due to the modes of transmission, respirators may be required when working with Aspergillus fumigatus. Fit testing and training is required annually per MSU’s Respiratory Program.