Characteristics
Morphology Gram negative microaerophilic curved rod.
Growth Conditions Nutrient rich media usually containing BSA or FBS.
Health Hazards
Host Range Humans and animals
Modes of Transmission  With more than 50 % of the world’s population infected, acquisition is likely to occur during childhood through fecal-oral, oral-oral contact, or during gastrointestinal tract transit disorders.
Signs and Symptoms  Gastroenteritis and ulcers. Major symptoms are abdominal pain, heartburn, and nausea.
Infectious Dose Unknown.
Incubation Period  Unknown.
Medical Precautions/Treatment
Prophylaxis None
Vaccines None
Treatment Clarithromycin, amoxicillin, and tetracycline.
Surveillance Can be confirmed by culture, blood antigen detection, and urease detection
MSU Requirements  Report any exposures.
Laboratory Hazards
Laboratory Acquired Infections (LAIs) 3 reported cases.
 Sources May be located in the oral cavity, gastrointestinal and hepatobiliary regions.
Supplemental References
BMBL:5th Edition http://www.cdc.gov/biosafety/publications/bmbl5/BMBL.pdf
Canadian MSDS http://www.phac-aspc.gc.ca/lab-bio/res/psds-ftss/index-eng.php
CDC https://www.cdc.gov/ulcer/files/hpfacts.PDF
Containment Requirements
BSL2 For all procedures involving known or potentially infected cultures.
ABSL2 For all procedures utilizing infected animals.
Spill Procedures
Small Notify others working in the lab. Remove and don new PPE. Cover area of the spill with absorbent material and add 10 % Bleach. Allow 30 minutes hour of contact time. After 30 minutes and then cleanup and dispose of materials.
Large For assistance, contact MSU's Biosafety Officer: Ryan Bartlett, ryan.bartlett@montana.edu, (406) 994-6821
or Safety and Risk Management (406-994- 2711).
Exposure Procedures
Mucous membrane
Flush eyes, mouth or nose for 5 minutes at eyewash station.
Other Exposures
Wash area with soap and water for 5 minutes.
Reporting
Immediately report incident to supervisor, complete a first report of injury report, and submit to Safety and Risk Management.
Medical Follow-up
During business hours: Bridger Occupational Health 3406 Laramie Drive. Weekdays 8am -6pm.  Weekends 9am-5pm
After business hours: Bozeman Deaconess Hospital Emergency Room 915 Highland Blvd Bozeman, MT
Viability
Disinfection Susceptible to 10 % Bleach, and 70 % ethanol.
Inactivation Inactivated by dry heat (1 hour at 160-170° C).
Survival Outside Host Unknown.
Personal Protective Equipment (PPE)
Minimum PPE Requirements At minimum, gloves, closed toed shoes, lab coat, and appropriate face and eye protection prior to working with H. pylori. Additional PPE may be required depending on lab specific SOPs. 
Additional Precautions None.