|Morphology||Swine Influenza A/H1N1. Family Orthomyxoviridae. Negative sense single-stranded RNA virus. Reassortment of strains of influenza A/H1N1 of avian, porcine and human origin. Virus capsid is enveloped. Virions are spherical to pleomorphic.|
Influenza viruses are cultured in chick embryo and cell culture (MDCK cells).
Humans, birds and other mammals (vertebrates).
|Modes of Transmission||Droplet infection, fomites, saliva, nasal secretions, feces, aerosol and blood.|
|Signs and Symptoms||Fever, runny nose, sore throat, diarrhea, coughing, vomiting, nausea, lethargy, myalgia, anorexia and dyspnea.|
|Incubation Period||Estimated incubation period is unknown and could range from 1-7 days.|
|Prophylaxis||Antiviral chemoprohylaxis with antiviral drugs.|
|Treatment||Oseltamivir, Zanamivir for seven days after exposure.|
|Surveillance||Daily temperature recording.|
|MSU Requirements||Report any exposures.|
|Laboratory Acquired Infections (LAIs)||None reported to date.|
|Sources||No data available.|
|BSL2||For all procedures involving known or potentially infected cultures.|
|ABSL2||For all procedures utilizing infected animals.|
|Small||Notify others working in the lab. Remove and don new PPE. Cover area of the spill with absorbent material and add 10 % Bleach. Allow 30 minutes hour of contact time. After 30 minutes and then cleanup and dispose of materials.|
|Large||For assistance, contact MSU's Biosafety Officer: Ryan Bartlett, firstname.lastname@example.org, (406) 994-6733
or Safety and Risk Management (406-994- 2711).
Flush eyes, mouth or nose for 5 minutes at eyewash station.
Wash area with soap and water for 5 minutes.
Immediately report incident to supervisor, complete a first report of injury report, and submit to Safety and Risk Management.
During business hours: Bridger Occupational Health 3406 Laramie Drive. Weekdays 8am -6pm. Weekends 9am-5pm
After business hours: Bozeman Deaconess Hospital Emergency Room 915 Highland Blvd Bozeman, MT
|Disinfection||70 % ethanol, 5 % Lysol, and 10 % bleach.|
|Inactivation||Influenza A is sensitive to treatment with heat, lipid solvents, non-ionic detergents, formaldehyde, oxidizing agents. The infectivity is reduced after exposure to irradiation.|
|Survival Outside Host||
Influenza viruses can remain infectious for about one week at human body temperature, over 30 days at 0° C, and indefinitely at very low temperatures
|Minimum PPE Requirements||At minimum, gloves, closed toed shoes, lab coat, and appropriate face and eye protection prior to working with InfluenzaA. Additional PPE may be required depending on lab specific SOPs|
|Additional Precautions||Due to the modes of transmission, respirators may be required when working with Influenza A. Fit testing and training is required annually per MSU’s Respiratory Program.|