|Morphology||Gram-positive facultative anaerobe that is usually found in pairs or chains.|
|Growth Conditions||Can be placed in various growth media and incubated at 37° C.|
|Host Range||Humans and Animals.|
|Modes of Transmission||Hand-to-mouth and aerosol transmission is common. 10-30% of women are positive in their genital tracts although the bacterium is normally a resident of the gastrointestinal tract.|
|Signs and Symptoms||Shaking chills, chest pain, dyspnea, fever, productive cough, and sinusitis. Can cause middle ear infections. Can progress to pneumonia, bacteremia, meningitis.|
|Incubation Period||For early onset disease, less than 7 days. For late onset disease, the incubation period is unknown.|
|Prophylaxis||Penicillin or ampicillin have been shown to reduce transmission and morbidity to the neonate|
|Surveillance||Monitor for symptoms of infection.|
|MSU Requirements||Report any exposures|
|Laboratory Acquired Infections (LAIs)||78 documented cases since 1999|
|Sources||Sputum, blood, respiratory secretions, throat swabs, parenteral inoculation.|
|BSL2||For all procedures involving known or potentially infected cultures.|
|ABSL2||For all procedures utilizing infected animals.|
|Small||Notify others working in the lab. Remove and don new PPE. Cover area of the spill with absorbent material and add 10 % Bleach. Allow 30 minutes hour of contact time. After 30 minutes and then cleanup and dispose of materials.|
|Large||For assistance, contact MSU's Biosafety Officer: Ryan Bartlett, firstname.lastname@example.org, (406) 994-6733
or Safety and Risk Management (406-994- 2711).
Flush eyes, mouth or nose for 5 minutes at eyewash station.
Wash area with soap and water for 5 minutes.
Immediately report incident to supervisor, complete a first report of injury report, and submit to Safety and Risk Management.
During business hours: Bridger Occupational Health 3406 Laramie Drive. Weekdays 8am -6pm. Weekends 9am-5pm
After business hours: Bozeman Deaconess Hospital Emergency Room 915 Highland Blvd Bozeman, MT
|Disinfection||Susceptible to 10 % Bleach, 70 % ethanol, and 2 % gluteraldehyde.|
|Inactivation||Inactivated by moist heat (15 minutes at 121° C) and dry heat (1 hour at 160-170° C).|
|Survival Outside Host||Has been found to survive months in dry dust in buildings. It can survive in milk at -20°C for 4 weeks and in fish tissues at 700C for at least 9 months.|
|Minimum PPE Requirements||At minimum, gloves, closed toed shoes, lab coat, and appropriate face and eye protection prior to working with S. agalactiae. Additional PPE may be required depending on lab specific SOPs.|
|Additional Precautions||All procedures that may produce aerosols, or involve high concentrations or large volumes should be conducted in a biological safety cabinet (BSC).|