Protocols and protocol modifications can be submitted to the IACUC at any time. Depending
on the nature of the protocol, some protocols and many protocol modifications can
be reviewed soon after they are received by the IACUC office using the designated
member review (DMR) process (found here). Note, however, that protocols and modifications involving category E animals,
survival surgeries, animal housing areas that are not part of the animal program overseen
by the IACUC, protocols that impact personnel safety, and initial protocols involving
USDA covered species cannot be reviewed by DMR and will be reviewed by the full IACUC
at the next monthly meeting.
For DMR, protocols will be reviewed by a DMR committee consisting of a minimum of
a reviewer designated by the IACUC Chair the Attending Veterinarian, and the IACUC
Chair. These reviewers assume the responsibility for the full committee in granting
unanimous approval, requiring modification, or sending the protocol or modification
back for full committee review. The assigned designated reviewers have a maximum
of two weeks to generate an outcome. Modifications to existing protocols are handled
in the same manner as a new protocol. Please remember that submission for DMR does
not guarantee DMR review, and you should plan accordingly to meet your project and
grant deadlines if full committee review is required.
The full IACUC meets once a month to review protocols and modifications and may approve,
require modification to secure approval, or withhold approval of protocols. If modifications
are required to secure final approval for a protocol reviewed by the full committee,
the IACUC also uses a similar DMR process, with the committee comprised of the primary
reviewer of the original protocol, the Attending Veterinarian, and the IACUC Chair.
All IACUC members, through the review and approval of these policies, have agreed
in writing, that the quorum of members present at a convened meeting may decide by
unanimous vote to use DMR subsequent to full committee review when modification is
needed to secure approval. Any member of the IACUC may, at any time, request to see
the revised protocol and/or request a full committee review of the protocol.
All protocols expire three years from the date of approval, and the IACUC does not
have the authority to administratively extend approval beyond that three year date.
The PI is responsible for submitting a new protocol three months in advance of expiration.