Care and Use Program
The IACUC protocol is the
written document that confirming Montana State University
adherence to federal animal welfare regulations and
ethical guidelines in the use of live animals for research,
testing or teaching. The IACUC reviews protocols to
assure that procedures are adequately described and
appropriately documented. Here are some of the most
common areas where the protocol documentation tends
to be inadequate:
- Project overview is not written in language understandable
to a lay audience or does not include adequate information
about the benefits associated with performing the
- Number of animals requested is not justified based
on the experimental design or the total numbers of
animals do not add up properly.
- The use of animals and/or the species selection
are inadequately justified.
- Research personnel are not adequately described.
- The literature searches for alternatives are not
- Description of the surgical procedures are incomplete,
lacking appropriate detail, or is inconsistent with
the experimental design.
- Expected clinical signs, potential for pain, discomfort
and distress, including the assessment criteria that
will be used for monitoring animals are not adequately
discussed or described.
- Post-procedural monitoring and care, including the
use of post-procedural analgesics are not presented.
- Inadequate or inappropriate detail of the actual
procedures involving live animals.
- Missing attachments to general protocol form.