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Etiology
No evidence is cited.
Epidemiology
No evidence is cited.
Diagnosis
Clinical Diagnosis
Body Mass Index (BMI) is a reliable
index to evaluate the body fat. (Click here for BMI
calculator or BMI
chart)
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Caveats
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Age group studied: 44-73y
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Type/size: Non-blinded series (74 patients)
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Population characteristics: All women
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Outcome measure: BMI, Broca index, bioelectrical
impedance analysis
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Not EBM
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Citations
Laboratory/X-ray Diagnosis
No evidence is cited.
Treatment
Behavioral/Cognitive Therapy
Of the cognitive strategies studied, cue
avoidance was the only technique with some evidence of effectiveness.
Extending the length of behavioral therapy also appeared to be more effective
when compared to an intervention of shorter duration. There was no evidence
to suggest that monetary contracting as an individual versus groups may
be of value in the weight loss process. It is possible that some
elements of a weight loss programme by correspondence may be useful, for
example, the provision of lessons and homework. The practice of daily
weight charting may be helpful for both weight loss and maintenance of
weight loss.
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Caveats
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Age group studied: All ages
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Type/size: Systematic review of 99 RCTs (most
<30 patients)
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Population characteristics: Unknown
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Outcome measure: Weight change, weight measures
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Citations
Diet Therapy
Combining very low calorie diets
(VLCDs) with behavioral therapy appears to be more effective than treating
obese adults with either VLCD or behavior therapy alone. There is no difference
in the effectiveness of fat restriction alone compared to fat and calorie
restriction in the longer term (i.e. at one year follow-up) in non-diabetics.
The restriction of both fat and calories may be helpful in the shorter
term. The provision of meal plans and grocery lists may be of benefit as
a weight loss intervention. There is no demonstration of the superiority
of either inpatient or outpatient management of obesity. The combination
of diet and exercise in conjunction with behavioral treatment, however,
does appear to be more beneficial for weight loss than diet alone. When
diet and exercise were combined in the absence of behavioural treatment,
the combination was no more effective than diet and exercise as single
interventions.
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Caveats
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Age group studied: All ages
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Type/size: Systematic review of 99 RCTs (most
<30 patients)
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Population characteristics: Unknown
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Outcome measure: Weight change, weight measures
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Citations
Increased dietary fibre does not appear
to show a greater mean weight loss when compared to a low fibre/low carbohydrate
diet. However, fibre supplements appear to be more effective than
placebo at increasing weight loss for subjects receiving a 1200 kcal/day
diet.
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Caveats
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Age group studied: All ages
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Type/size: Systematic review of 99 RCTs (most
<30 patients)
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Population characteristics: Unknown
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Outcome measure: Weight change, weight measures
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Citations
Exercise
Exercise appeared to be of benefit
when compared to a group receiving no exercise. The evidence for the effectiveness
of exercise versus dietary education remains unclear, although both these
treatment conditions had superior weight losses at the end of the weight
loss intervention compared to a no-treatment control.
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Caveats
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Age group studied: All ages
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Type/size: Systematic review of 99 RCTs (most
<30 patients)
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Population characteristics: Unknown
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Outcome measure: Weight change, weight measures
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Citations
Pharmacotherapy
Pharmacological interventions did
not appear to be effective in producing sustained long term weight loss.
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Caveats
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Age group studied: All ages
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Type/size: Systematic review of 99 RCTs (most
<30 patients)
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Population characteristics: Unknown
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Outcome measure: Weight change, weight measures
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Citations
Phenylpropanolamine is safe and effective
for weight loss (0.14-0.27 kg/wk when compared to placebo), appears less
effective than prescription anorectics in studies exceeding 4 wk, and weight
loss was not enhanced by combination with benzocaine.
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Caveats
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Age group studied: Unknown
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Type/size: Meta-analysis (5 trials)
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Population characteristics: Unknown
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Outcome measure: Weight loss and side effects
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Citations
There is no scientific evidence that human
chorionic gonadotropin (hCG), as used in the Simeons therapy, causes
weight-loss, a redistribution of fat, staves off hunger or induces a feeling
of well-being.
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Caveats
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Age group studied: Unknown
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Type/size: Meta-analysis (24 studies)
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Population characteristics: Obese patients
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Outcome measure: Weight-loss, fat-redistribution,
hunger, feeling of well-being
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Citations
Surgery
There is good evidence to indicate the
effectiveness of gastric bypass in the treatment of morbidly obese
patients (those with BMI>40). However, surgery is associated with complications.
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Caveats
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Age group studied: All ages
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Type/size: Systematic review of 99 RCTs (most
<30 patients)
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Population characteristics: Unknown
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Outcome measure: Weight change, weight measures
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Citations
Other Therapies
No clear picture emerges to show that
acupuncture
or acupressure is effective in reducing appetite
or body weight.
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Caveats
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Age group studied: Unknown
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Type/size: Systematic review of 4 RCTs (270
participants)
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Population characteristics: Two trials involved
obese volunteers, one trial involved volunteers and one trial involved
obese women
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Outcome measures: Body weight reduction; appetite
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Citations
Monitoring/Maintenance
The majority of the studies demonstrate
weight
regain either during treatment or post-intervention. The addition of
self-help peer groups in addition to therapist led booster sessions was
shown to be effective in maintaining weight loss. However, after the maintenance
program ended, weight regain occurred. One of the most effective maintenance
programs consisted of behavioral therapy and continued therapist contact
by mail and telephone. The involvement of the family or spouse in both
weight loss and maintenance phases appeared to be of some benefit, although
the differences in treatment effect were not statistically significant.
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Caveats
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Age group studied: All ages
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Type/size: Systematic review of 99 RCTs (most
<30 patients)
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Population characteristics: Unknown
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Outcome measure: Weight change, weight measures
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Citations
Prognosis
In women, higher levels of adiposity within
the "normal" range, as assessed by the body mass index, were associated
with an increased risk for fatal and nonfatal coronary heart disease
(CHD). Even modest weight gains after 18 years of age were also associated
with a higher risk for CHD.
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Caveats
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Age group studied: 30-55y
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Type/size: 14 year cohort study of 115818
patients
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Population characteristics: Female nurses
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Outcome measure: CHD including symptomatic
non-fatal MI or fatal CHD
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Citations
High levels of obesity indicators, such as
body mass index (BMI) and skinfold thickness, are only slightly associated
with an excess mortality and that overweight and obesity are health
hazards only if they are accompanied by an elevation of other risk factors,
mainly of blood pressure. The minimum risk for men is around 28 units of
BMI, and it decreased to smaller levels of body mass index after the exclusion
of smokers, people carrying severe diseases at entry and/or those who died
during the first 5 years of the study. The analysis of skinfold thickness
showed similar but less clear-cut results. Among women, due to the limited
number of fatal events, the analysis was unable to show any clear relationship
of body mass index or skinfold thickness to all-causes mortality.
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Caveats
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Age group studied: 30-69 years
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Type/size: Meta-analysis (studies of 8,341
men and 1,100 women)
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Population characteristics: Males and females
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Outcome measure: All-cause mortality
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Citations
Prevention/Intervention
General practice-based health programs,
consisting of brief or intensive advice, have a modest and variable effect
on health outcomes. These interventions show promise in effecting
small changes in behavior.
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Caveats
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Age group studied: Unknown
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Type/size: Meta-analysis (23 studies, 10 of
dietary interventions)
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Population characteristics: general practice
patients
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Outcome measure: Various lifestyle changes
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Citations
Patient Education
The following patient education materials
are consistent with the available evidence.
Rev. 8/1/01
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