Selected Publications for John A. Mercer, Ph.D.
Stauffer, E.A., Scarborough, J.D., Hirono, M., Miller, E.D., Shah, K., Mercer, J.A., Holt, J.R., and Gillespie, P.G. (2005). Fast adaptation in vestibular hair cells requires myosin-1c Activity. Neuron 47: 541-553. (Download PDF)
D.W. Provance, C.R. Gourley, C.M. Silan, L.C. Cameron, K.M. Shokat, J.R. Goldenring, K.Shah, P.G. Gillespie, and J.A. Mercer (2004). Chemical-genetic inhibition of a sensitized mutant myosin-Vb demonstrates a role in peripheral-pericentriolar membrane traffic. Proc. Nat. Acad. Sci., 101, 1868-1873. (Download PDF)
J.R. Holt, S.K.H. Gillespie, D.W. Provance, K. Shah, K. M. Shokat, D.P. Corey, J.A. Mercer and P.G. Gillespie (2002). A chemical-genetic strategy implicates myosin-1c in adaptation by hair cells. Cell 108, 371-381. (Download PDF)
Provance, D.W., T. James and J.A. Mercer (2002). Melanophilin, the product of the leaden locus, is required for targeting of myosin-Va to melanosomes. Traffic 3, 124-132.
Gillespie P.G., J.P. Albanesi, M. Bahler, W.M. Bement, J.S. Berg, D.R. Burgess, B. Burnside, R.E. Cheney, D.P. Corey, E. Coudrier, P. de Lanerolle, J.A. Hammer, T. Hasson, J.R. Holt, A.J. Hudspeth, M. Ikebe, J. Kendrick-Jones, E.D. Korn, R. Li, J.A. Mercer, R.A. Milligan, M.S. Mooseker, E.M. Ostap, C. Petit, T.D. Pollard, J.R. Sellers, T. Soldati and M.A. Titus (2001). Myosin-I nomenclature. Journal of Cell Biology 155, 703-4.
Lapierre LA, R. Kumar, C.M. Hales, J. Navarre, S.G. Bhartur, J.O. Burnette, D.W. Provance., J.A. Mercer, M. Bähler, and J.R. Goldenring (2001). Myosin Vb is associated with plasma membrane recycling systems. Molecular Biology of the Cell 12, 1843-1857.
Mercer, J.A. (2000). Intercellular junctions: downstream and upstream of Ras? Seminars in Cell and Developmental Biology.
Walikonis R.S., O.N. Jensen, M. Mann, D.W. Provance, J.A. Mercer, and M.B. Kennedy (2000) Identification of proteins in the postsynaptic density fraction by mass spectrometry. Journal of Neuroscience 20, 4069-4080.
Reck-Peterson, S.L., D.W. Provance, M.S. Mooseker, and J.A. Mercer (2000). Class V myosins. Biochim Biophys Acta. 1496, 36-51.
Gillespie, P.G., S.K.H. Gillespie, J.A. Mercer, K. Shah and K.M. Shokat (1999). Engineering of the myosin-I beta nucleotide-binding pocket to create selective sensitivity to N6-modified ADP analogs. Journal of Biological Chemistry 274, 31373-31381.
Zhadanov, A.B., D.W. Provance Jr., C.A. Speer, D. Goss, J.A. Blixt, J.D. Coffin, C.M. Reichert and J.A. Mercer (1999). Absence of the tight junctional protein AF-6 disrupts epithelial cellúcell junctions and cell polarity during mouse development. Current Biology 9, 880-888. (Abstract, QuickTime motion pictures wild-type and mutant cells).
Provance, D.W., and J.A. Mercer (1999). Myosin-V: head to tail. Cellular and Molecular Life Sciences 56, 233-242.
Provance, D.W., M. Wei, V. Ipe and J.A. Mercer (1996). Cultured melanocytes from dilute mutant mice exhibit dendritic morphology and altered melanosome distribution. Proceedings of the National Academy of Sciences (USA) 93, 14554-14558.
Whitmer, J.D., J.S. Koslovsky, M. Bähler and J.A. Mercer (1996). Chromosomal location of three unconventional myosin heavy chain genes in the mouse. Genomics 38 235-237.
Zhao, L.P., J.S. Koslovsky, J. Reinhard, M. Bähler, A.E. Witt, D.W. Provance and J.A. Mercer (1996). Cloning and characterization of myr 6, an unconventional myosin dilute/myosin-V family. Proceedings of the National Academy of Sciences (USA) 93, 10826-10831.(Download PDF)
Seperack, P.K., J. A. Mercer, M.C. Strobel, N.G. Copeland and N.A. Jenkins (1995). Retroviral sequences located within an intron of the dilute gene alter dilute expression in a tissue-specific manner. EMBO Journal 14, 2326-2332.
Mercer, J.A., J.P. Albanesi and S.T. Brady (1994). Molecular motors and cell motility in the brain. Brain Pathology 4, 167-179.
Koslovsky, J.S., C. Qian, X. Jiang and J.A. Mercer (1993). Molecular cloning of a mouse myosin I expressed in brain. FEBS Letters 320, 121-124.
Mercer, J.A., P.K. Seperack, M.C. Strobel, N.G. Copeland and N.A. Jenkins (1991). Novel myosin heavy chain encoded by murine dilute coat color locus. Nature 349, 709-713.
Perkins, A.S., J.A. Mercer, N.A. Jenkins and N.G. Copeland (1991). Patterns of Evi-1 expression in embryonic and adult tissues suggest that Evi-1 plays an important regulatory role in mouse development. Development 111, 479-487.
Brannan, C.I., D.J. Gilbert., J.D. Ceci, Y. Matsuda, V.M. Chapman, J.A. Mercer, H. Eisen,, L.A. Johnston, N.G. Copeland and N.A. Jenkins (1992). An interspecific linkage map of mouse chromosome 15 positioned with respect to the centromere. Genomics 13, 1075-1081.
Feldman, A.M., P.E. Ray, C.M. Silan, J.A. Mercer, W. Minobe and M.R. Bristow (1991). Selective gene expression in the failing human heart. Quantification of steady-state levels of mRNA in endomyocardial biopsies using the polymerase chain reaction. Circulation 83, 1866-1872.
Mercer, J.A., N.A. Jenkins and N.G. Copeland (1990). Lack of ecotropic virus involvement in induction of lymphomas in DBA/2J mice by 7,12-dimethylbenz(a)anthracene. Journal of Virology 64, 5199-5203.
Mercer, J.A., K.H. Lee, B.A. Nexo, N.A. Jenkins and N.G. Copeland. (1990). Mechanism of chemical activation of expression of the endogenous ecotropic murine leukemia provirus Emv-3. Journal of Virology 64, 2245-2249.
Siracusa, L.D., C.M. Silan, M.J. Justice, J.A. Mercer, A.R. Bauskin, Y. Ben-Neriah, D. Duboule, N.D. Hastie, N.G. Copeland, and N.A. Jenkins. (1990). A molecular genetic linkage map of mouse chromosome 2. Genomics 6, 491-504.
Jenkins, N.A., M.C. Strobel, P.K. Seperack, D.M. Kingsley, K.J. Moore, J.A. Mercer, L.B. Russell and N.G. Copeland (1989). A retroviral insertion in the dilute (d) locus provides molecular access to this region of mouse chromosome 9. Progress in Nucleic Acid Research and Molecular Biology 36, 207-220.
Keshet, E., M.P. Rosenberg,, J.A. Mercer, F. Propst, G.F. Vande Woude, N.A. Jenkins, and N.G. Copeland (1988). Developmental regulation of ovarian-specific Mos expression. Oncogene 2, 235-240.
Mercer, J.A., C.A. Wiley and D.H. Spector (1988). Pathogenesis of MCMV infection: identification of infected cells in the spleen during acute and latent infection. Journal of Virology 62, 987-993.
Mercer, J.A. and D.H. Spector (1986). Pathogenesis of murine cytomegalovirus infection in resistant and susceptible strains of mice. Journal of Virology 57, 497-504.
Marks, J.R., J.A. Mercer and D.H. Spector (1983). Transcription in mouse embryo cells permissively infected by murine cytomegalovirus. Virology 131, 247-254.
Mercer, J.A., J.R. Marks, and D.H. Spector (1983). Molecular cloning and restriction endonuclease mapping of the murine cytomegalovirus genome. Virology 129, 94-106.
Mercer, J.A. and D.R. Soll. (1980). Complexity and reversibility of the timer for the onset of aggregation in Dictyostelium. Differentiation 16, 117-124.
Stauffer, E.A., Scarborough, J.D., Hirono, M., Miller, E.D., Shah, K., Mercer, J.A., Holt, J.R., and Gillespie, P.G. (2005). Fast adaptation in vestibular hair cells requires myosin-1c Activity. Neuron 47: 541-553. (Download PDF)
D.W. Provance, C.R. Gourley, C.M. Silan, L.C. Cameron, K.M. Shokat, J.R. Goldenring, K.Shah, P.G. Gillespie, and J.A. Mercer (2004). Chemical-genetic inhibition of a sensitized mutant myosin-Vb demonstrates a role in peripheral-pericentriolar membrane traffic. Proc. Nat. Acad. Sci., 101, 1868-1873. (Download PDF)
J.R. Holt, S.K.H. Gillespie, D.W. Provance, K. Shah, K. M. Shokat, D.P. Corey, J.A. Mercer and P.G. Gillespie (2002). A chemical-genetic strategy implicates myosin-1c in adaptation by hair cells. Cell 108, 371-381. (Download PDF)
Provance, D.W., T. James and J.A. Mercer (2002). Melanophilin, the product of the leaden locus, is required for targeting of myosin-Va to melanosomes. Traffic 3, 124-132.
Gillespie P.G., J.P. Albanesi, M. Bahler, W.M. Bement, J.S. Berg, D.R. Burgess, B. Burnside, R.E. Cheney, D.P. Corey, E. Coudrier, P. de Lanerolle, J.A. Hammer, T. Hasson, J.R. Holt, A.J. Hudspeth, M. Ikebe, J. Kendrick-Jones, E.D. Korn, R. Li, J.A. Mercer, R.A. Milligan, M.S. Mooseker, E.M. Ostap, C. Petit, T.D. Pollard, J.R. Sellers, T. Soldati and M.A. Titus (2001). Myosin-I nomenclature. Journal of Cell Biology 155, 703-4.
Lapierre LA, R. Kumar, C.M. Hales, J. Navarre, S.G. Bhartur, J.O. Burnette, D.W. Provance., J.A. Mercer, M. Bähler, and J.R. Goldenring (2001). Myosin Vb is associated with plasma membrane recycling systems. Molecular Biology of the Cell 12, 1843-1857.
Mercer, J.A. (2000). Intercellular junctions: downstream and upstream of Ras? Seminars in Cell and Developmental Biology.
Walikonis R.S., O.N. Jensen, M. Mann, D.W. Provance, J.A. Mercer, and M.B. Kennedy (2000) Identification of proteins in the postsynaptic density fraction by mass spectrometry. Journal of Neuroscience 20, 4069-4080.
Reck-Peterson, S.L., D.W. Provance, M.S. Mooseker, and J.A. Mercer (2000). Class V myosins. Biochim Biophys Acta. 1496, 36-51.
Gillespie, P.G., S.K.H. Gillespie, J.A. Mercer, K. Shah and K.M. Shokat (1999). Engineering of the myosin-I beta nucleotide-binding pocket to create selective sensitivity to N6-modified ADP analogs. Journal of Biological Chemistry 274, 31373-31381.
Zhadanov, A.B., D.W. Provance Jr., C.A. Speer, D. Goss, J.A. Blixt, J.D. Coffin, C.M. Reichert and J.A. Mercer (1999). Absence of the tight junctional protein AF-6 disrupts epithelial cellúcell junctions and cell polarity during mouse development. Current Biology 9, 880-888. (Abstract, QuickTime motion pictures wild-type and mutant cells).
Provance, D.W., and J.A. Mercer (1999). Myosin-V: head to tail. Cellular and Molecular Life Sciences 56, 233-242.
Provance, D.W., M. Wei, V. Ipe and J.A. Mercer (1996). Cultured melanocytes from dilute mutant mice exhibit dendritic morphology and altered melanosome distribution. Proceedings of the National Academy of Sciences (USA) 93, 14554-14558.
Whitmer, J.D., J.S. Koslovsky, M. Bähler and J.A. Mercer (1996). Chromosomal location of three unconventional myosin heavy chain genes in the mouse. Genomics 38 235-237.
Zhao, L.P., J.S. Koslovsky, J. Reinhard, M. Bähler, A.E. Witt, D.W. Provance and J.A. Mercer (1996). Cloning and characterization of myr 6, an unconventional myosin dilute/myosin-V family. Proceedings of the National Academy of Sciences (USA) 93, 10826-10831.(Download PDF)
Seperack, P.K., J. A. Mercer, M.C. Strobel, N.G. Copeland and N.A. Jenkins (1995). Retroviral sequences located within an intron of the dilute gene alter dilute expression in a tissue-specific manner. EMBO Journal 14, 2326-2332.
Mercer, J.A., J.P. Albanesi and S.T. Brady (1994). Molecular motors and cell motility in the brain. Brain Pathology 4, 167-179.
Koslovsky, J.S., C. Qian, X. Jiang and J.A. Mercer (1993). Molecular cloning of a mouse myosin I expressed in brain. FEBS Letters 320, 121-124.
Mercer, J.A., P.K. Seperack, M.C. Strobel, N.G. Copeland and N.A. Jenkins (1991). Novel myosin heavy chain encoded by murine dilute coat color locus. Nature 349, 709-713.
Perkins, A.S., J.A. Mercer, N.A. Jenkins and N.G. Copeland (1991). Patterns of Evi-1 expression in embryonic and adult tissues suggest that Evi-1 plays an important regulatory role in mouse development. Development 111, 479-487.
Brannan, C.I., D.J. Gilbert., J.D. Ceci, Y. Matsuda, V.M. Chapman, J.A. Mercer, H. Eisen,, L.A. Johnston, N.G. Copeland and N.A. Jenkins (1992). An interspecific linkage map of mouse chromosome 15 positioned with respect to the centromere. Genomics 13, 1075-1081.
Feldman, A.M., P.E. Ray, C.M. Silan, J.A. Mercer, W. Minobe and M.R. Bristow (1991). Selective gene expression in the failing human heart. Quantification of steady-state levels of mRNA in endomyocardial biopsies using the polymerase chain reaction. Circulation 83, 1866-1872.
Mercer, J.A., N.A. Jenkins and N.G. Copeland (1990). Lack of ecotropic virus involvement in induction of lymphomas in DBA/2J mice by 7,12-dimethylbenz(a)anthracene. Journal of Virology 64, 5199-5203.
Mercer, J.A., K.H. Lee, B.A. Nexo, N.A. Jenkins and N.G. Copeland. (1990). Mechanism of chemical activation of expression of the endogenous ecotropic murine leukemia provirus Emv-3. Journal of Virology 64, 2245-2249.
Siracusa, L.D., C.M. Silan, M.J. Justice, J.A. Mercer, A.R. Bauskin, Y. Ben-Neriah, D. Duboule, N.D. Hastie, N.G. Copeland, and N.A. Jenkins. (1990). A molecular genetic linkage map of mouse chromosome 2. Genomics 6, 491-504.
Jenkins, N.A., M.C. Strobel, P.K. Seperack, D.M. Kingsley, K.J. Moore, J.A. Mercer, L.B. Russell and N.G. Copeland (1989). A retroviral insertion in the dilute (d) locus provides molecular access to this region of mouse chromosome 9. Progress in Nucleic Acid Research and Molecular Biology 36, 207-220.
Keshet, E., M.P. Rosenberg,, J.A. Mercer, F. Propst, G.F. Vande Woude, N.A. Jenkins, and N.G. Copeland (1988). Developmental regulation of ovarian-specific Mos expression. Oncogene 2, 235-240.
Mercer, J.A., C.A. Wiley and D.H. Spector (1988). Pathogenesis of MCMV infection: identification of infected cells in the spleen during acute and latent infection. Journal of Virology 62, 987-993.
Mercer, J.A. and D.H. Spector (1986). Pathogenesis of murine cytomegalovirus infection in resistant and susceptible strains of mice. Journal of Virology 57, 497-504.
Marks, J.R., J.A. Mercer and D.H. Spector (1983). Transcription in mouse embryo cells permissively infected by murine cytomegalovirus. Virology 131, 247-254.
Mercer, J.A., J.R. Marks, and D.H. Spector (1983). Molecular cloning and restriction endonuclease mapping of the murine cytomegalovirus genome. Virology 129, 94-106.
Mercer, J.A. and D.R. Soll. (1980). Complexity and reversibility of the timer for the onset of aggregation in Dictyostelium. Differentiation 16, 117-124.
