College of Engineering seminar: Multiscale characterization of the mechanics of biological materials
- Thursday, March 9, 2017 from 1:00pm to 2:00pm
- Strand Union Building - view map
Sarah Calve, Ph.D. assistant professor at Purdue University, will speak on how biological materials are heterogeneous in composition and geometry from the micro to the macroscale. This heterogeneity leads to variations in mechanical properties at the different scales, indicating that cells can experience a different loading environment from the bulk tissues in which they reside. The scale of the biomechanical question being addressed will dictate the modality of mechanical testing; identification of engineering materials to replace bulk tissue (e.g. prosthetics) can be done using traditional axial loading experiments, whereas characterization of fibrillar scaffolds that aim to direct cellular behavior need to be conducted at a much finer scale (e.g. atomic force microscopy). Using examples from the literature and my own research, Calve will discuss the how the mechanical properties of biological materials are characterized from the single molecule to the tissue level, with a special focus on the extracellular matrix and the musculoskeletal system.
- College of Engineering