Department of Chemistry and Biochemistry Seminar
- Friday, October 26, 2018 at 3:10pm
- Chemistry & Biochemistry Building, Byker - view map
Dr. John Kozarich (ActivX Biosciences, Inc., La Jolla, CA) will present "Nucleotide Acyl Phosphates: Remarkable Chemoproteomic Interrogators of Nucleotide Binding Space."
John W. Kozarich is Distinguished Scientist, Executive Advisor and Board Director of ActivX Biosciences, Inc., La Jolla, CA. In 2001, John joined ActivX, a start-up company specializing in the design of chemoproteomic tools for drug discovery and development, and has served as its Chairman and President for most of that time, stepping down in April 2017.
John received a B.S. in Chemistry from Boston College (summa cum laude, Phi Beta Kappa, Scholar of the College) and a Ph.D. in Biological Chemistry from MIT (NSF Predoctoral Fellow) with Sidney Hecht. Following postdoctoral research in biochemistry at Harvard (NIH Postdoctoral Fellow) with Jack Strominger, he entered the ranks of academia (1977-94), ultimately holding full professorships in Pharmacology at Yale University School of Medicine and in Chemistry & Biochemistry at the University of Maryland, College Park. A sabbatical in 1990 as CSO of a start-up biotech company Alkermes (ALKS), in Cambridge, MA motivated him to explore other venues for his chemical interests. In 1992, he joined Merck Research Labs as Vice President of Biochemistry, having responsibility for a broad array of drug discovery programs and biotechnology collaborations and for the initial development of Merck’s Boston Research Center.
His research over the years has focused on the mechanisms of enzyme and drug action. He has served on many advisory committees in the academic, professional society, government and business sectors. He was an American Cancer Society Faculty Research Awardee (1983-88) and received the Pfizer Award in Enzyme Chemistry (1988) by the American Chemical Society. He is a Fellow of the American Association for the Advancement of Science, a recipient of the Distinguished Scientist Award of the San Diego Section of the American Chemical Society (2009), and was named a Director of the Year (2014) by the Corporate Directors Forum for his Board leadership of Ligand Pharmaceuticals (LGND). In addition to his role at ActivX, he is Chairman of the Board at Ligand Pharmaceuticals, Chief Scientific Advisor at Kyorin Pharmaceutical Co. (Tokyo), Chairman of the Board of Intec Pharma (Jerusalem), Past Chair of the Board of Trustees of the Gordon Research Conferences, and Adjunct Professor of Chemical Physiology at The Scripps Research Institute.
- Department of Chemistry and Biochemistry