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Species Maximum Blood Withdrawal
Mouse 0.1 ml per 10 grams body weight
Rat 1 ml per 100 grams body weight
Hamster/Gerbils 0.6 ml per 100 grams body weight
Rabbit 10 ml per kg
Nonhuman Primate 10 ml per kg

 

These stated volumes are the maximum blood to be withdrawn in a single bleed. At maximum, it can be repeated at two-week intervals. If more frequent bleeding is needed, the volume should be proportionally reduced. If more blood than this maximum volume is needed, the investigator must consult with the Veterinarian and receive IACUC approval.