Science is our Medicine
Explore our research
Mechanisms of bacterial defense andviral counter-defense
We aim to understand the mechanisms that bacteria use to defend themselves from phage infection and counter mechanisms that phages use to subvert bacterial immune systems. Much of the lab focuses on CRISPR systems but we are also interested in other immune pathways. Read more about our research.
Our most recent publications
- Cas1 and the Csy complex are opposing regulators of Cas2/3 nuclease activity
- Structure Reveals Mechanisms of Viral Suppressors that Intercept a CRISPR RNA-Guided Surveillance Complex
- Using Cryoem to Understand How Phages Evade Bacterial CRISPR Defense System
- CRISPR control of virulence in Pseudomonas aeruginosa
Laina Hall and Pushya Krishna selected for the 2021 Barry M Goldwater Scholarships
Undergraduate researchers Laina Hall and Pushya Krishna won the prestigious Barry M Goldwater scholarship.
Pictured with mentors Dr. Wiedenheft (left) and Andrew Santiago-Frangos (right).
The Barry Goldwater Scholarship and Excellence in Education Foundation was established by Congress in 1986 to serve as a living memorial to honor the lifetime work of Senator Barry Goldwater.
This is awarded to to college sophomores and juniors who intend to pursue research careers in the natural sciences.
CRISPR's under the big sky
Dr. Jennifer Doudna- Winner the Stibitz and Wilson award
CRISPR conference 2017 was held in Big Sky, Montana
Research in the Wiedenheft lab is supported by
- The National Institutes of Health Grants (INBRE, P20GM103500, P30GM110732-03, R01GM110270, and R01GM108888)
- National Science Foundation EPSCoR (Grant EPS-110134)
- The M. J. Murdock Charitable Trust
- The Gordon and Betty Moore Foundation
- A young investigator award from Amgen
- The Montana State University Agricultural Experimental Station
- Montana University System Research Initiative (51040-MUSRI2015-03)