Bimczok Lab - Bimczok Lab | Montana State University

The majority of human and veterinary pathogens target the mucosal surfaces of the body. These mucosal sites need to maintain a delicate balance between appropriately responding to virulent pathogens and avoiding unnecessary inflammatory responses to harmless agents. The Bimczok laboratory is interested in the complex interplay between pathogens, mucosal antigen-presenting cells, and epithelial cells. The overarching goal of our work is to better understand how epithelial responses to bacteria and viruses lead to alterations in the function of antigen-presenting cells such as dendritic cells and macrophages, and how this immune cell-epithelial cell crosstalk defines the outcome of infection.

To address these research goals, we utilize:

Primary mucosal cells and tissues
Organoid and tissue chip models
A large animal model
Transgenic mouse models

Current projects, funded by the NIH and USDA:

Helicobacter pylori infection in the human gastric mucosa
SARS-CoV-2 infection in human and bat intestine
Mycoplasma ovipneumoniae infection in sheep

Recent Highlights

	Teg gave a great talk at CRWAD in Chicago! January 2023
	New publication: our collaborative work with the Apple lab! September 2022

Events

January 23, 2023 @ 4:45pm

Tegner presenting at Conference for Research Workers in Animal Disease (CRWAD)
Chicago, IL

February 3, 2023 @ 1pm

Tegner's Research in Progress Seminar
Leon Johnson Hall 346

April 18-20, 2023

Association for Clinical and Translational Science - Translational Science 2023
Washington, DC

April 20-23, 2023

American Physiology Summit
Long Beach, CA

May 6-9, 2023

Digestive Disease Week
Chicago, IL