Virus and dsRNA-triggered transcriptional responses reveal key components of honey bee antiviral defense.

Brutscher LM, Daughenbaugh KF, Flenniken ML.

Sci Rep. 2017 Jul 25;7(1):6448. doi: 10.1038/s41598-017-06623-z.

Pathways to zoonotic spillover.

Plowright RK, Parrish CR, McCallum H, Hudson PJ, Ko AI, Graham AL, Lloyd-Smith JO.

Nat Rev Microbiol. 2017 Aug;15(8):502-510. doi: 10.1038/nrmicro.2017.45. Epub 2017 May 30. Review.

Structure Reveals Mechanisms of Viral Suppressors that Intercept a CRISPR RNA-Guided Surveillance Complex.

Chowdhury S, Carter J, Rollins MF, Golden SM, Jackson RN, Hoffmann C, Nosaka L, Bondy-Denomy J, Maxwell KL, Davidson AR, Fischer ER, Lander GC, Wiedenheft B.

Cell. 2017 Mar 23;169(1):47-57.e11. doi: 10.1016/j.cell.2017.03.012.

Models of Eucalypt phenology predict bat population flux.

Giles JR, Plowright RK, Eby P, Peel AJ, McCallum H.

Ecol Evol. 2016 Sep 21;6(20):7230-7245. eCollection 2016 Oct.

Synthesis of Five- and Six-Membered N-Phenylacetamido Substituted Heterocycles as Formyl Peptide Receptor Agonists.

Vergelli C, Schepetkin IA, Ciciani G, Cilibrizzi A, Crocetti L, Giovannoni MP, Guerrini G, Iacovone A, Kirpotina LN, Ye RD, Quinn MT.

Drug Dev Res. 2017 Feb;78(1):49-62. doi: 10.1002/ddr.21370. Epub 2016 Nov 18.

Disease introduction is associated with a phase transition in bighorn sheep demographics.

Manlove K, Cassirer EF, Cross PC, Plowright RK, Hudson PJ.

Ecology. 2016 Oct;97(10):2593-2602. doi: 10.1002/ecy.1520. Epub 2016 Sep 19.

Null Mutations of Group A Streptococcus Orphan Kinase RocA: Selection in Mouse Infection and Comparison with CovS Mutations in Alteration of In Vitro and In Vivo Protease SpeB Expression and Virulence.

Feng W, Minor D, Liu M, Li J, Ishaq SL, Yeoman C, Lei B.

Infect Immun. 2016 Dec 29;85(1). pii: e00790-16. doi: 10.1128/IAI.00790-16. Print 2017 Jan.

Abiotic and biotic factors affecting the replication and pathogenicity of bee viruses.

McMenamin AJ, Brutscher LM, Glenny W, Flenniken ML.

Curr Opin Insect Sci. 2016 Aug;16:14-21. doi: 10.1016/j.cois.2016.04.009. Epub 2016 Apr 26. Review.

Contemporary Pharyngeal and Invasive emm1 and Invasive emm12 Group A Streptococcus Isolates Exhibit Similar In Vivo Selection for CovRS Mutants in Mice.

Feng W, Liu M, Chen DG, Yiu R, Fang FC, Lei B.

PLoS One. 2016 Sep 9;11(9):e0162742. doi: 10.1371/journal.pone.0162742. eCollection 2016.

Modulation of Human Neutrophil Responses by the Essential Oils from Ferula akitschkensis and Their Constituents.

Schepetkin IA, Kushnarenko SV, Özek G, Kirpotina LN, Sinharoy P, Utegenova GA, Abidkulova KT, Özek T, Başer KH, Kovrizhina AR, Khlebnikov AI, Damron DS, Quinn MT.

J Agric Food Chem. 2016 Sep 28;64(38):7156-70. doi: 10.1021/acs.jafc.6b03205. Epub 2016 Sep 13.


Synthesis and Pharmacological Evaluation of Indole Derivatives as Deaza Analogues of Potent Human Neutrophil Elastase Inhibitors.

Crocetti L, Schepetkin IA, Ciciani G, Giovannoni MP, Guerrini G, Iacovone A, Khlebnikov AI, Kirpotina LN, Quinn MT, Vergelli C.

Drug Dev Res. 2016 Sep;77(6):285-99. doi: 10.1002/ddr.21323. Epub 2016 Jul 30.

Therapeutic Potential of Polyphenols from Epilobium Angustifolium (Fireweed).

Schepetkin IA, Ramstead AG, Kirpotina LN, Voyich JM, Jutila MA, Quinn MT.

Phytother Res. 2016 Aug;30(8):1287-97. doi: 10.1002/ptr.5648. Epub 2016 May 24. Review.

Differential Type I Interferon Signaling Is a Master Regulator of Susceptibility to Postinfluenza Bacterial Superinfection.

Shepardson KM, Larson K, Morton RV, Prigge JR, Schmidt EE, Huber VC, Rynda-Apple A.

MBio. 2016 May 3;7(3). pii: e00506-16. doi: 10.1128/mBio.00506-16.

2-Arylacetamido-4-phenylamino-5-substituted pyridazinones as formyl peptide receptors agonists.

Vergelli C, Schepetkin IA, Ciciani G, Cilibrizzi A, Crocetti L, Giovannoni MP, Guerrini G, Iacovone A, Kirpotina LN, Khlebnikov AI, Ye RD, Quinn MT.

Bioorg Med Chem. 2016 Apr 8. pii: S0968-0896(16)30253-X. doi: 10.1016/j.bmc.2016.04.019. [Epub ahead of print]

Pathogen prevalence and abundance in honey bee colonies involved in almond pollination.

Cavigli I, Daughenbaugh KF, Martin M, Lerch M, Banner K, Garcia E, Brutscher LM, Flenniken ML.

Apidologie. 2016;47:251-266. Epub 2015 Oct 21.

Effects of the neutrophil elastase inhibitor EL-17 in rat adjuvant-induced arthritis.

Di Cesare Mannelli L, Micheli L, Cinci L, Maresca M, Vergelli C, Pacini A, Quinn MT, Paola Giovannoni M, Ghelardini C.

Rheumatology (Oxford). 2016 Jul;55(7):1285-94. doi: 10.1093/rheumatology/kew055. Epub 2016 Mar 30.

A novel dual NO-donating oxime and c-Jun N-terminal kinase inhibitor protects against cerebral ischemia-reperfusion injury in mice.

Atochin DN, Schepetkin IA, Khlebnikov AI, Seledtsov VI, Swanson H, Quinn MT, Huang PL.

Neurosci Lett. 2016 Apr 8;618:45-49. doi: 10.1016/j.neulet.2016.02.033. Epub 2016 Feb 26.

A novel persulfide detection method reveals protein persulfide- and polysulfide-reducing functions of thioredoxin and glutathione systems.

Dóka É, Pader I, Bíró A, Johansson K, Cheng Q, Ballagó K, Prigge JR, Pastor-Flores D, Dick TP, Schmidt EE, Arnér ES, Nagy P.

Sci Adv. 2016 Jan 22;2(1):e1500968. doi: 10.1126/sciadv.1500968. eCollection 2016 Jan.

RNAi and Antiviral Defense in the Honey Bee.

Brutscher LM, Flenniken ML.

J Immunol Res. 2015;2015:941897. doi: 10.1155/2015/941897. Epub 2015 Dec 21. Review.


Roles of Toll-Like Receptor 2 (TLR2), TLR4, and MyD88 during Pulmonary Coxiella burnetii Infection.

Ramstead AG, Robison A, Blackwell A, Jerome M, Freedman B, Lubick KJ, Hedges JF, Jutila MA.

Infect Immun. 2016 Mar 24;84(4):940-9. doi: 10.1128/IAI.00898-15. Print 2016 Apr.