Department of Chemistry and Biochemistry Graduate Student Seminar
- Thursday, December 13, 2018 at 12:00pm
- Chemistry & Biochemistry Building, Byker - view map
Ms. Ece Topuzlu will present "Biophysical and Surface Characterization of Plastic Degrading Polyesterases" in a graduate student seminar.
Abstract: Recalcitrance to natural degradation of synthetic plastics such as poly(ethylene terephthalate) (PET) is problematic in the world’s ecosystems. Several cutinases isolated from fungal species have been shown to enzymatically degrade PET to a limited extent. The discovery of Ideonella sakaiensis, and its ability to grow on PET as a major carbon source has led to the identification of two of the key enzymes responsible for hydrolysis of PET. These enzymes, named PETase and MHETase, act in a concerted manner to convert PET into its monomers and building blocks, respectively. This seminar will highlight the enzymatic capabilities of PETase on industrially relevant substrates, its localization in cells in vivo, and its synergistic activity with MHETase for PET degradation.
- Doreen Brown