Department of Chemistry and Biochemistry Seminar
- Friday, March 15, 2019 at 3:10pm
- Chemistry & Biochemistry Bldg, Byker Auditorium - view map
Dr. Orion Berryman (University of Montana, Dept. of Chemistry and Biochemistry) will present "Anion Triple Helicates: Self-Assembly Directed by Halogen Bonding."
Abstract: Anion directed self-assembly is inherently challenging in part due to the diffuse nature of anions and their variable binding geometries. In particular, the self-assembly of higher order anion helicates in solution is extremely rare. However, halogen bonding offers unique opportunities to address these challenges. Here we present the first triple helicates that bind and encapsulate iodide and bromide in solution, as well as the solid state.1 The helicates self-assemble from three cationic arylethynyl strands that present a tubular anion channel lined with nine inwardly directed halogen bond donors (Figure 1). These robust assemblies are stable in solution even at elevated temperature which has allowed us to provide the first kinetic and mechanistic studies on anion based higher-order helicates.2 Additionally, we have demonstrated that the hydrogen bond enhanced halogen bond is a novel tactic to control preorganization3 and we will present ongoing efforts using this strategy to develop functional helical structure and new organocatalysts.
- Department of Chemistry and Biochemistry