Kopriva Science Seminar Series: Brian Pettygrove
- Wednesday, January 26, 2022 at 1:00pm
- Chemistry & Biochemistry Bldg, Byker Auditorium - view map
Brian Pettygrove, a doctoral candidate in microbiology in the Department of Microbiology and Cell Biology, will present "Characterization of host-pathogen interactions during early Staphylococcus aureus biofilm formation on surfaces" at 1:00 p.m. on Wednesday, Jan. 26, in the Byker Auditorium in the Chemistry and Biochemistry Building and Webex. The lecture is free and open to the public. A reception will follow.
Microbes commonly live in surface-associated communities called biofilms that are distinct in structure, physiology, and behavior from free-floating planktonic communities. Biofilms can cause various serious infections such as chronic wounds and infections of permanently implanted medical devices. While they are relatively rare, infections to implanted biomaterials can be devastating and often require implant removal to resolve the infection.
There is a good understanding of how biofilms tolerate antibiotics and host immune defenses during a biomaterial infection; however, it remains unclear how contaminating microbes initially evade the immune system. Brian Pettygrove is involved in a research program at MSU studying the early immune response following biomaterial implantation to determine how the model organism Staphylococcus aureus overcomes immune defenses. The goal is that this work will eventually result in new prophylactic treatment strategies.
An endowment created by Phil Kopriva, a 1957 microbiology graduate from MSU, funds the Kopriva Science Seminar Series. Kopriva also created an endowment to fund the Kopriva Graduate Fellowship Program, which provides support and opportunities for graduate students in the College of Letters and Science, particularly in the biomedical sciences. The series features four to six seminars annually, with talks provided by MSU graduate students, faculty members, and guest speakers. For more information about this and other Kopriva lectures, visit www.montana.edu/lettersandscience/kopriva/or call 406-994-4288.
- Amanda Smith